In order to study the effects of different environmental loads on the dynamic response of the wind-fishery farming platform, a floating wind-fishery farming platform equipped with flexible farming system with different mesh densities is taken as the research object, and the basic hydrodynamic performance is studied based on the potential flow theory. By OrcaFlex software, the coupling numerical model of the floating wind-fishery farming platform is established, and the time-domain coupling dynamic analysis is carried out, so as to get the results of the dynamics response. The results show that: the natural periods of heave, pitch and roll of the floating wind-fishery farming platform can avoid the common wave period; the farming system is of great influence on the heave, pitch and mooring line tension of the platform, but is of little influence on the heave of the platform; compared with the wind speed and wave period, the current speed is of more significant effect on the dynamic response of the platform.