In order to study the wind resistance performance of offshore platform derricks under strong typhoon, a method combining static analysis and transient dynamic analysis is proposed, which comprehensively considers three wind directions: back wind, lateral wind, and 45° wind. The Davenport power spectrum is used, and the harmonic superposition method and fast Fourier technology are used to simulate the pulsating wind field. The corresponding wind speed time history curve is obtained through MATLAB programming, which is converted into wind load and loaded onto the model. The time history curves of the maximal displacement, axial stress and bending moment of the nodes are obtained. It is found that the 45° wind direction is the more unfavorable wind direction for the derricks, and the bottom and root of the derricks are heavily loaded. In dynamic analysis, the displacement and stress results of the 45° wind direction are nearly three times that of the static analysis. Therefore, transient analysis method is recommended for future production practice.