In order to study the influence of various parameters on the dynamic response of floating wind power equipment and find the rule of response change and direction of design optimization, an integrated simulation is conducted according to the parameters of HZ 6.2 MW floating wind power equipment. Combined with the specification requirements, design experience and environmental conditions, the return period of different environmental conditions, wind spectrum type, wave spectrum type and extreme gust period are selected to proceed sensitivity analysis, and the dynamic response results of different parts of the floating wind power equipment are obtained. The results show that: the return period and combination of different environmental conditions are of obvious effects on the motion response and mooring tension, while the effects on the wind turbine load are related to the state of the wind turbine; the wind spectrum type mainly affects the the wind turbine load, but is of little influence on the platform motion and mooring tension and the turbulent wind spectrum with spatial coherence is the most dangerous; the wave spectrum type is of great influence on the motion amplitude and extreme mooring tension, is of little influence on the wind turbine load under the production condition, but is of great influence under the idling condition; the gust period is of obvious effect on motion response, tower load and nacelle acceleration, but is of little effect on hub load and mooring tension.