Based on the multi-source data of offshore wind turbine monitoring system, including the dynamic response data of tower and foundation structure, unit operation data and on-site environmental data, the statistical characteristics of the structural response under different conditions are analyzed to reveal the influence of environment and operation conditions on the structure dynamic response. The results show that: the vibration acceleration response of the wind turbine structure is dominated by the side direction of the engine room coordinate system; when the wind speed reaches the rated wind speed, the vibration acceleration response intensity reaches the maximum, and then decreases with the further increase of wind speed; the vibration acceleration response intensity at the top of the tower is greater than that at other measuring points in the parked conditions, startup/stop transition condition and low rotational speed condition, while the vibration acceleration response intensity at the middle of the tower is the largest in the variable speed condition and rated rotational condition. When monitoring the vibration of offshore wind turbine structures, there should be a focus on the variation of acceleration response characteristics at the top and middle of the wind turbine tower in the offshore wind turbine monitoring system.